Keywords
adult
Touba
Senegal Introduction
How to Cite
Abstract
Introduction :
Malaria is still a major public health problem. The severe forms are not uncommon ; Moreover, the Covid-19 pandemic has added to the current endemo-epidemic context of malaria.
Aim :
to determine the hospital prevalence of severe malaria, its epidemiological, diagnostic and prognostic profile in the context of the Covid-19 pandemic. Materials and Method: This was a retrospective, descriptive study of patients hospitalized for severe malaria at the Serigne Mbacké Madina Health Center in Touba between 1 July and 31 October 2019 and 2020.
Results :
The prevalence of severe malaria was 14.2% 90/633) during the study period with 10.0% (34/338) in 2019 and 18.3% in 2020 (56/295). The mean age was 33.8 ± 17.3 years. Male sex constituted 61.1% (n =55), i.e. a sex ratio of 1.57. During the months of October we recorded the highest number of cases 77.8%. Almost all patients 91.1% (n=82) were brought in by family members. The mean time between the onset of symptoms and the consultation was 4.6 days. Prostration was found in 73.3% (n = 66), followed by cardiovascular collapse in 11.1% (n = 10) and coma in 7.8% (n = 7). More than half of patients (55.6%) had a fever of 38.5 ° C and above. The comorbidities were dominated by diabetes 43.7% (n=7) and hypertension 37.5% (n=6). The mean parasite density was 14,542 trophozoites per mm3 and there was a statistical relationship between hospital stay and parasite density (p = 0.010). Severe anemia (<7g / dl) was noted in 5 patients. Thrombocytopenia was found in 42.2% of cases (n=38). The only antimalarial used before an oral switch was Artesunate by injection. Probabilistic antibiotic treatment was started in 17 patients (19.8%). Ciprofloxacin in 76.5% (n =13) was the most commonly used antibiotic. The average length of hospital stay was 3.18 ± 0.89 days with extremes of 1 and 6 days. The lethality was 2.2% (n =2).
Conclusion :
Severe malaria remains a major public health issue to date, despite significant progress in its management. Prevention is yet to be reinforced as well as early hospital consultation to reduce the morbidity and mortality of this disease.
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Copyright (c) 2026 N Ngom, M Faye, M Doutchi, F Faye, M Fall, A Ba, D Thioub, M Dia, L Diouf, N Diop, A Ndiaye, O Ka