Keywords
Infections
spermogram
sperm culture Niamey
How to Cite
Abstract
Introduction :
Infections are a major cause of male infertility. The asymptomatic nature of certain germs delays treatment, leading to often irreversible consequences. The aim of this study was to investigate the spermiological and bacteriological aspects of sperm at the Magori polyclinic in Niamey.
Materials and method :
This was a cross-sectional descriptive study with retrospective and prospective data collection from November 1, 2022 to October 31, 2023. All patients who underwent spermogram, sperm culture and/or sperm PCR at the Magori polyclinic in Niamey were included. For the spermogram, the SCA evolution system was used (semi automated analysis). Gene Xpert and conventional bacteriology were used. Data analysis was performed using Sphinx software version 5.1.0.4, and data entry was performed using Microsoft Office (Excel and Word 2019).
Results :
A total of 71 patients were included in the study, including 56 with retrospective data collection. In 15 patients, data were collected prospectively. Mean age was 37.2 ±8.4 years, with extremes of 18 and 60 years. Ninety-five percent of patients (n=68) were married, 88% of whom (n=60) were monogamous. Infertility was primary in 66.2% (n=47). Oligozoospermia represented 26.8% (n=19) and azoospermia 19.7% (n=14). Sperm culture was positive in 21.1% of cases (n=16). Staphylococcus aureus was found in 60% of cases (n=9).
Conclusion :
The use of spermograms to study sperm parameters in the investigation of male infertility is well established. In this work, we have listed the various abnormalities observed on spermograms in a population of men, most of whom were seen for infertility tests. We also combined sperm culture and PCR with the spermogram.
References
1. Chiware TM, Vermeulen N, Blondeel K, 2299B Farquharson R, Kiarie J, Lundin K, et al. IVF and other ART in low- and middle-income countries: a systematic landscape analysis. Hum Reprod Update. 2021;27(2):213-28.
2. Bhattacharya I, Sharma SS, Majumdar SS. 2300B Etiology of Male Infertility: an Update. Reprod Sci. 2024;31(4):942-65.
3. Somé NE, Da DC, Boncoungou J, 2301B Lankoandé J, Poda JN. Who is responsible for couple infertility: A clinic-based survey in Ouagadougou (Burkina Faso). International Journal of Nursing and Midwifery. 2017;9(2):10-6.
4. Oghbaei H, Rastgar Rezaei Y, Nikanfar S, 2302B Zarezadeh R, Sadegi M, Latifi Z, et al. Effects of bacteria on male fertility: Spermatogenesis and sperm function. Life Sci. 2020 ;256 :117891. https://doi.org/10.1016/j.lfs.2020.117891
5. Henkel R, Offor U, Fisher D. The role of 2303B infections and leukocytes in male infertility. Andrologia. 2021 ;53(1) : e13743. https://doi.org/10.1111/and.13743
6. Henkel R. Leukocytospermia and/or 2304B Bacteriospermia: Impact on Male Infertility. J Clin Med. 2024 ;13(10) : 2841. https://doi.org/10.3390/jcm13102841
7. Farsimadan M, Motamedifar M. Bacterial 2305B infection of the male reproductive system causing infertility. J Reprod Immunol. 2020;142:103183. https://doi.org/10.1016/j.jri.2020.103183
8. Rodrigues R, Sousa C, Vale N. Chlamydia 2306B trachomatis as a Current Health Problem: Challenges and Opportunities. Diagnostics (Basel).2022 ;12(8) : 1795. https://doi.org/10.3390/diagnostics12081795
9. Halidou M, Magagi IA, Zakou ARH, Kodo 2307B A, Adamou H, Amadou S. Infertilité Masculine à l’Hôpital National de Zinder : Aspects Épidémiologiques et Cliniques : Male infertility at the National Hospital of Zinder : Epidemiology and clinical features. Health Sci Dis. 2022 ;23(3):85-9.
10. Abebe MS, Afework M, Abaynew Y. 2308B Primary and secondary infertility in Africa: systematic review with meta-analysis. Fertil Res Pract. 2020 ;6(1):20. Disponible sur: https://doi.org/10.1186/s40738-020-00090-3
11. Kbirou A, Jandou I, Adnane E, Mohammed 2309B E, Moataz A, Mohammed D, et al. Profil épidémiologique et clinique de l’infertilité masculine: étude observationnelle transversale descriptive et analytique. Sexologies. 2022 ;31(2):117-22.
12. Nwajiaku LA, Mbachu II, Ikeako L. 2310B Prevalence, Clinical Pattern and Major Causes of Male Infertility in Nnewi, South East Nigeria: A Five Year Review. Afrimedic Journal. 2012;3(2):16-9.
13. Sefogah PE, Otchere LN, Yarney L, Baku 2311B AA, Adzei FA. Exploring the Psychological Experiences Of Women With Infertility In Urban Ghana: A Qualitative Study: Psychological Experiences of Women with Infertility. Postgraduate Medical Journal of Ghana. 2023;12(2):69-73. Disponible sur: https://doi.org/10.60014/pmjg.v12i2.336
14. Wischmann T, Thorn P. (Male) infertility: 2312B what does it mean to men? New evidence from quantitative and qualitative studies. Reprod Biomed Online. 2013;27(3):236-43.
15. Niang L, Ndoye M, Labou I, Jalloh M, Kane 2313B R, Diaw JJ, et al. Profil épidémiologique et clinique de l’infertilité masculine à l’hôpital général de Grand-Yoff, Sénégal : à propos de 492 cas. Basic Clin Androl. 2009 ;19(2) :103-7.
16. Mongane J, Hendwa E, Sengeyi D, 2314B Kajibwami E, Kampara F, Chentwali S, et al. Association between bacterial vaginosis, Chlamydia trachomatis infection and tubal factor infertility in Bukavu, Democratic Republic of Congo. BMC Infectious Diseases. 2024 ;24(1):480. https://doi.org/10.1186/s12879-024-09379-w
17. Abdullah AA, Ahmed M, Oladokun A. 2315B Prevalence of infertility in Sudan: A systematic review and meta-analysis. Qatar Med J. 2021 ;2021(3) :47. https://doi.org/10.5339/qmj.2021.47
18. Ikyernum JA, Agbecha A, Hwande ST. 2316B Semen Profile of Men Presenting with Infertility at First Fertility Hospital Makurdi, North Central Nigeria. Clinical Medicine and Diagnostics. 2019 ;9(2):26-35.
19. Huang B, Wang Z, Kong Y, Jin M, Ma L. 2317B Global, regional and national burden of male infertility in 204 countries and territories between 1990 and 2019: an analysis of global burden of disease study. BMC Public Health. 2023;23(1):2195. https://doi.org/10.1186/s12889-023-16793-3
20. Rotondo JC, Lanzillotti C, Mazziotta C, 2318B Tognon M, Martini F. Epigenetics of Male Infertility: The Role of DNA Methylation. Front Cell Dev Biol. 2021 ;9 :689624 : https://doi.org/10.3389/fcell.2021.689624
21. Saint F, Huyghe E, Methorst C, Priam A, 2319B Seizilles De Mazancourt E, Bruyère F, et al. Infections et infertilité masculine. Progrès en Urologie. 2023 ;33(13) :636-52.
22. Zeyad A, Hamad M, Amor H, Hammadeh 2320B ME. Relationships between bacteriospermia, DNA integrity, nuclear protamine alteration, sperm quality and ICSI outcome. Reprod Biol. 2018 ;18(1) :115-21.
23. Berjis K, Ghiasi M, Sangy S. Study of 2321B seminal infection among an infertile male population in Qom, Iran, and its effect on sperm quality. Iran J Microbiol. 2018 ;10(2) :111-6.
24. Esmailkhani A, Akhi MT, Sadeghi J, 2322B Niknafs B, Zahedi Bialvaei A, Farzadi L, et al. Assessing the prevalence of Staphylococcus aureus in infertile male patients in Tabriz, northwest Iran. Int J Reprod Biomed. 2018;16(7):469-74.
25. Kirakoya B, Barnabé Z, Karim PA, Aristide 2323B KF, Clotaire Y, Amélie N. Epidemiological and Clinical Profile of Male Hypofertility in Consultation at the Urology-Andrology of Yalgado Ouedraogo Teaching Hospital (Burkina Faso). Advances in Sexual Medicine. 2014;5(1):1-6. Disponible sur: http://dx.doi.org/10.4236/asm.2015.51001
26. Ramezani M, Hakimi H, Zainodini N, 2324B Rahnama A, Sayadi A. Survey on the Prevalence of Chlamydia trachomatis and Neisseria gonorrhoeae Infections and Their Possible Effects on Seminal Quality in Infertile Men. Int J Infect. 2019 ;6(4) : e101243. https://doi.org/10.5812/iji.101243
27. Moazenchi M, Totonchi M, Salman Yazdi R, 2325B Hratian K, Mohseni Meybodi MA, Ahmadi Panah M, et al. The impact of Chlamydia trachomatis infection on sperm parameters and male fertility: A comprehensive study. Int J STD AIDS. 2018 ;29(5) :466-73.
28. Qing L, Song QX, Feng JL, Li HY, Liu G, 2326B Jiang HH. Prevalence of Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium and Ureaplasma urealyticum infections using a novel isothermal simultaneous RNA amplification testing method in infertile males. Ann Clin Microbiol Antimicrob. 2017 ;16(1):45. https://doi.org/10.1186/s12941-017-0220-2.
Metrics
Downloads
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright (c) 2026 I Hamani, B Marou Soumana, I Hamadou, B Issa Oumarou, N Hama Aghali, L Yadji Guero, A Baraze Son Allah, A Attinine Soumana, C Oniboukou Rolande, S Azombakin, M Boutchi