Abstract
Introduction :
Malaria, by its severity and its economic and social consequences, is a major public health problem in tropical countries including Niger. It is the leading cause of pediatric death in Niger. The objective of this study was to investigate the factors associated with malaria in infants aged 0 to 6 months at the Amirou Boubacar Diallo National Hospital in Niamey.
Material and methods :
This was a retrospective study over a period of two (2) years, carried out in the pediatric department of the National Hospital Amirou Boubacar Diallo. The study population consisted of children aged 0 to 6 months. The proportions were compared using Pearson's Chi-square statistical test at the 5% significance level.
Results :
The prevalence was 46.98% (n= 460). Children under 3 months were in the majority with 57.3%. The male gender predominated with 56.4%. The socioeconomic level of the parents was average in 85%. Fever was the main reason for consultation with 79.1%. Malnutrition was noted in 60% of patients. The most common complication was anemia with 61%. Almost all of the children, 96.8%, had received artesunate as basic treatment. A mortality of 6.1% was recorded. The risk of onset of malaria was high in the event of nonexclusive breastfeeding, low maternal age and malnutrition (OR>1).
Conclusion :
Due to its morbidity and mortality, malaria remains a threat to the pediatric population, especially the youngest. Control must consider the identified risk factors.
References
1. Organisation Mondiale de la Santé (OMS). Rapport 2021 sur le paludisme dans le monde, Principaux messages. Genève 2021, 24p.
2. World Health Organization. Guideline for the treatment of malaria. 3rd edition. WHO: Geneva, Switzerland 2015, 318p.
3. Ibrahim ML, Labbo R, Mahamane ML, Arzika I, Boubacar M, Amadou S, et al. Cours National de Paludologie au Niger : Bilan de cinq ans. J Appl Biosci 2017 ; 116 : 12-8
4. Ministère de la Santé Publique (MSP). Annuaire des statistiques sanitaires du Niger, année 2019. Niamey : MSP 2019, 241p.
5. Imbert P, Banerjee A. Paludisme de l’enfant. Encycl Méd Chir, Pédiatrie, 4-320-A-20, Maladies infectieuses 2002 ; 8-507-A-30.
6. Doolan DL, Dobano C, Baird JK. Acquired immunity to malaria. Clin Microbiol Rev 2009 ; 22 : 13-36.
7. Asse KV, Plo KJ, Yenan JP, Yeboua YK, Aka KA, Yao KC. Le paludisme du nourrisson âgé de 1 à 6 mois : étude rétrospective à propos de 50 cas colligés en 2013 à Bouaké (Côte d’Ivoire). J Pediatr Puericult 2015 ; 28 : 1-6.
8. Segbo GG, Alao MJ, d’Almeida M, Lalya F, Ayivi B. Infection Bactérienne au cours du Paludisme Grave Chez le Nourrisson de Moins de Six Mois au Centre National Hospitalier et Universitaire (CNHU) de Cotonou, Bénin. Clinics in Mother and Child Health 2011; 8: 1-4.
9. Doolan DL, Dobano C, Baird JK. Acquired immunity to malaria. Clin Microbiol Rev 2009; 22: 13-36.
10. Azagoh-Kouadio R, Enoh SJ, Kassi Kondo F, Cisse L, Sinde KC, Couitchere L et al. Paludisme de l’enfant : prise en charge au chu de Treichville. Sc méd –RISM 2017 ; 19(1) : 26-30.
11. Chaca C, Seydou F, Hamadoun S, Sidibé KA, Kandioura T, Dembélé KH. Prise en charge des cas de paludisme chez les enfants de 0 à 5 ans et perception des mères dans un service de pédiatrie à Bamako. Mali Med 2012 ; 28 (3) :1-6.
12. Dicko-Traoré F, Sylla M, Djimdé AA, Diakité AA, Diawara M, Togo B et al. Le paludisme congénital et néonatal en Afrique subsaharienne, un évènement rare ? J Pediatr Puericult 2011 ; 24 : 57- 61.
13. Nicholas FB, Martine T, Landry K, Dyna K, Jean Lambert C, Bienvenu K et al. Exclusive Breastfeeding and Clinical Malaria Risk in 6-Month-Old Infants: A Cross-Sectional Study from Kinshasa, Democratic Republic of the Congo. Am J Trop Med Hyg 2016; 95(4): 827– 30.
14. Oldenburg CE, Guerin PJ, Berthé F, Grais RF, Isanaka S. Malaria and Nutritional Status Among Children With Severe Acute Malnutrition in Niger: A Prospective Cohort Study. Clinical Infectious Diseases 2018 ; 67 : 102-7.
15. Brazeau NF, Tabala M, Kiketa L, Kayembe D, Chalachala JL, Kawende B et al. Exclusive Breastfeeding and Clinical Malaria Risk in 6-Month-Old Infants: A Cross-Sectional Study from Kinshasa, Democratic Republic of the Congo. Am J Trop Med Hyg 2016 ; 95(4): 827-30.
16. Kalanda BF, Verhoeff FH, Brabin BJ. Breast and complementary feeding practices in relation to morbidity and growth in Malawian infants. Eur J Clin Nutr 2006; 60: 401–407.
17. Das D, Grais RF, Okiro EA, Stepniewska K, Mansoor R, Van der kam S et al. Complex interactions between malaria and malnutrition: a systematic literature review. BMC Medicine 2018; 16:186.
18. Kinyoki DK, Moloney GM, Uthman OA. Comorbidity of malnutrition with falciparum malaria parasitaemia among children under the aged 6–59 months in Somalia: a geostatistical analysis. Infectious Diseases of Poverty 2018; 7:72.
19. Alkasoum I, Daou M, Doutchi M, Boubacar S, Maman Anou M, Lamine MM et al. Interaction between Malnutrition and Severe Malaria among Children at the National Hospital of Niamey-Niger. International Journal of Research and Reports in Hematology 2018 ; 1(2) : 1-6.
20. Roulet M, Cheseaux M, Coti P. Conséquences de la dénutrition chez l’enfant et l’adolescent. Mortalité, morbidité, conséquences médicoéconomiques. Nutr Clin Metabol 2005 ; 19(4):207-13.
21. Kamaye M, Alido S, Seyni F, Moumouni G, Aboubacar S, Maman O. Facteurs associés au décès chez les enfants atteints de paludisme grave à l’hôpital national de Niamey. J Afr Pediatr Genet Med 2019 ; 7 : 38-43.
22. Adedemy J, Agossou J, Alao M, Noudamadjo A, Ayivi B. Rôle de l’anémie sévère et de l’hypoglycémie dans la mortalité du paludisme grave de l’enfant en milieu hospitalier à Parakou (Benin). Mali Med 2015 ; 30(1) :19-24.
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Copyright (c) 2026 Z Abdoulaye, I Alkassoum, A Samaila, M Doussou, A Goni, A Menietou, S Djibo, S Alido
