Keywords
Co-infections
virus
AIDS
HIV
hepatitis
HBV
HCV
How to Cite
Abstract
Introduction :
Coinfections by HIV and hepatitis B and/or C viruses are common and expose to serious complications because of their reciprocal interactions. The objective of this study was to determine its frequency and characteristics at the infectious diseases department of the Point G University Hospital in Mali.
Methods :
This was a one-year prospective, descriptive, and analytical study including all patients coinfected with HIV and hepatitis B and/or C viruses. Data were analyzed with SPSS v 20.0 software.
Results :
out of 203 HIV patients, 39 had HIV and HBV co-infection, i.e. 16.7%, and 5 had HIV-HCV co-infection, i.e. 3%. The modal age group was 31-45 years with 44.1% for HIVHBV co-infection and 50% for HIV-HCV co-infection. Men were the most represented in HIV-HBV co-infection (64.7%), while women were in HIV-HCV co-infection (66.7%). Pallor was the most common symptom in HIV/HBV and HIV/HCV coinfections, with 61.8% and 66.7%. ALTs were elevated in 14.7% of HIV/HBV co-infections and 33.3% of HIV/HCV co- infections. In most patients, CD4 counts were below 200 cells/mm3 and viral load was detectable.
Conclusion :
The co-infections of HIV with hepatitis B and C is relatively common and bear an increased risk of complications. Their management is problematic in our context; hence emphasis should be put on awareness and prevention.
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