The burden of typhoid perforation of the small intestine in Niger.
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Keywords

Typhoid perforation
socioeconomic status
peritonitis
financial burden
cost

How to Cite

1.
Adamou H, Amadou Magagi I, Adakal O, Abdoulaye M, Doutchi M, Hamidine I, et al. The burden of typhoid perforation of the small intestine in Niger. J Sah Sci Santé [Internet]. 2021 Dec. 1 [cited 2026 Oct. 14];1(2):131-9. Available from: https://www.j3s-fss-uas.org/index.php/jsss/article/view/14

Abstract

Objective :
to describe the epidemiological, economic and prognostic aspects of the management of non-traumatic perforation of the small intestine (PNTIG) of typhoid origin in the regions of Maradi and Zinder in Niger.

Materials and method :
This was a retrospective bicentric study over a period of 6 years from January 2014 to December 2019) in the emergency department of the National Hospital of Zinder and the Regional Hospital Center (CHR) of Maradi in Niger. . Inclusion concerned all patients operated on for peritonitis by non-traumatic perforation of the small intestine suspected to be typhoid.

Results :
During the study period, 6,254 surgical acute abdomens were operated on, including 68.3% of peritonitis (n = 4271). Typhoid-induced PNTIG accounted for 46.9% (n = 2931). The median age of the patients was 11 years (IIQ: 7-17). Children made up over 72% (n = 2113). The male sex was 64.2% (n = 1881) or a sex ratio of 1.79. Rural origin represented 67.4% (n = 1976) and the indigent constituted 71.3% of cases (n = 2090). Geographic accessibility was difficult in 63.2% (n = 1852). The mean time to admission was 114.84 ± 62.2 hours. The mean time to intervention was 8.96 ± 4.5 hours. An ileostomy was performed in 61.3% (n = 1797). The average cost of emergency care was 192,500 ± 69,500 FCFA. The average cost of restoring digestive continuity was 124,500 ± 35,000 FCFA. The overall mortality was 11.2% (n = 328). It was significantly associated with long admission times before consultation and before surgery (p <0.005). The following variables were also statistically associated with mortality: socioeconomic status of indigent (OR=1.66; p=0.0023) rural origin (OR=1.47; p=0.021) and accessibility geographic difficult (OR=1.44; p=0.031).

Conclusion :
Perforation of the small intestine of typhoid origin is very common in our setting. This tragedy often affects vulnerable children from disadvantaged rural and socio-economic backgrounds. The financial burden associated with care is enormous and unbearable for households; hence the urgency to put in place an effective prevention and care system.

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Copyright (c) 2026 H Adamou, I Amadou Magagi, O Adakal, M Abdoulaye, M Doutchi, I Hamidine, M Rouga, L Sani Madjiri, M Maikassoua, O Habou, L James Didier, R Sani