Factors associated with childhood malaria and prognostic aspects at Maradi regional hospital, Niger.
PDF (French)

Keywords

Severe malaria
anemia
cerebral malaria
child
Maradi
Niger

How to Cite

1.
Harouna Amadou M, Rabiou Kaka L, Kadri S, Hachimou A, Ibrahim A, Ibrahim Mamadou A, et al. Factors associated with childhood malaria and prognostic aspects at Maradi regional hospital, Niger. J Sah Sci Santé [Internet]. 2022 Dec. 31 [cited 2026 Oct. 14];2(2):431-7. Available from: https://www.j3s-fss-uas.org/index.php/jsss/article/view/53

Abstract

Objective :
To study the epidemiological, diagnostic and prognostic aspects of severe malaria in children at the CHR of Maradi.

Patients and method :
This was a cross-sectional and descriptive study for the period from July 1 to October 31, 2021. Included were children aged 0-15 years admitted to the Maradi CHR for severe malaria.

Results :
From July 1 to October 31, 2021 (4 months), 1040 children were hospitalized in the pediatric departments of the Maradi regional hospital; the diagnosis of severe malaria was made in 406 patients meeting the inclusion criteria, i.e. 39.3%. Severe anemia (hb<5g/dl) was the clinical manifestation of severe malaria most frequently found in our patients (58%), followed by convulsions (28.6%). The average duration of hospitalization was 7 days with extremes ranging from 0 days to 45 days. The evolution was favorable in 93.3% patients. Five patients (0.5%) were discharged with neurological s overall lethality was 6.7%. These were mainly children with severe anemia, neurological disorders such as seizures, severe malnutrition and respiratory distress.

Conclusion :
Severe childhood malaria is a public health problem due to its frequency, its clinical polymorphism and its evolution. Deaths relate mainly to anemic and neurological forms. Reducing malaria mortality is based both on an improvement in the nutritional status of children and a good transfusion policy as well as an improvement in resuscitation and prevention measures.

PDF (French)
References

1. Organisation Mondial de la santé (OMS). Rapport sur le paludisme dans le monde en clin d’œil 2019. http://www.who.int.

2. White NJ. Severe malaria. Malar J. 2022 Oct 6;21(1):284. doi: 10.1186/s12936-022-04301-8.

3. Organisation Mondial de la santé (OMS). Niger rapport annuel 2014. https://www.afro.who.int/publications/rap port-annuel-2014-oms-niger

4. Keita M, Coulibaly S, Samaké D, Cissoko Y, Keita BS, Traoré H et al. Paludisme Grave chez l’Enfant dans le District de Bamako: Aspects Épidémiologiques, Clinicobiologiques et Thérapeutiques: Paludisme grave chez l’enfant dans le district de Bamako. HEALTH SCI DISEASE. 2022;23(4) : 30-33.

5. Mansour MA, Samaila B, Mahamane ML, Mahamadou D, Ramatoulaye HL, Ibrahim A. Facteurs associés au paludisme grave de l’enfant et son pronostic à l’hôpital National de Niamey, Niger. Med Afrique Noire. 2019;66(8/9):466-76.

6. Camara B, Diouf S, Diagne I, Fall L, Ba A, Ba M, et al. Le paludisme grave de l’enfant en milieu hospitalier sénégalais. Med Mal Infect. 2003;33(1):45-8.

7. Atanda H, Porte J, Bon JC, Rodier D, Senga P. Mortalité et morbidité infantiles sur une population d’un service médical à PointeNoire (RPC). Rev Pédiatrie. 1991;27(3):101-6.

8. Castella F, Legros F, Lagardère B, Danis M. Paludisme d’importation chez l’enfant en France métropolitaine: accès simples, accès graves, et comparaison avec les accès de l’adulte. Bull CNRMI. 1999;15:37-46.

9. Imbert P, Candido D, Ka S, Sartelet I, Baujat G, Rogier C. Paludisme grave de l’enfant en zone de transmission saisonnière basse au Sénégal: influence de l’âge sur les manifestations cliniques. Dakar Méd. 1997;42:44-8.

10. Lagardère B. Le paludisme de l’enfant en 1990. Rev Prat. 1990;40(28):2591-4.

11. Lignes directrices de Organisation mondiale de la Santé (OMS) sur le paludisme - 16 février 2021 - World Health Organization (WHO). WHO/UCN/GMP/2021.01. https://apps.who.int/iris/bitstream/handle/ 10665/344167/WHO-UCN-GMP-2021.01-fre.pdf?sequence=1&isAllowed=y

12. Camara B, Diouf S, Diagne I, Fall L, Ba A, Ba M, et al. Le paludisme grave de l’enfant en milieu hospitalier sénégalais. Médecine Mal Infect. 2003;33(1):45-8.

13. Marsh K, English M, Crawley J, Peshu N. The pathogenesis of severe malaria in African children. Ann Trop Med Parasitol. 1996;90(4):395-402.

14. Shikur B, Deressa W, Lindtjørn B. Association between malaria and malnutrition among children aged underfive years in Adami Tulu District, southcentral Ethiopia: a case–control study. BMC Public Health. 2016;16(1):174.

15. McDonald CM, Olofin I, Flaxman S, Fawzi WW, Spiegelman D, Caulfield LE, et al. The effect of multiple anthropometric deficits on child mortality: meta-analysis of individual data in 10 prospective studies from developing countries. Am J Clin Nutr. 2013;97(4):896-901.

16. Ferreira E d’Avila, Alexandre MA, Salinas JL, Siqueira AM, Benzecry SG, Lacerda MV, et al. Association between anthropometrybased nutritional status and malaria: a systematic review of observational studies. Malar J. 2015;14(1):346. 1

17. Chiabi A, Tchokoteu PF, Toupouri A, Mbeng TB, Wefuan J. The clinical spectrum of severe malaria in children in the east provincial hospital of Bertoua, Cameroon. Bull-Soc Pathol Exot. 2004;97:239-43.

18. Gbadoé AD, Kini-Caussi M, Koffi S, Traoré H, Atakouma DY, Tatagan-Agbi K, et al. Évolution du paludisme grave de l’enfant au Togo de 2000 à 2002. Médecine Mal Infect. 2006;36(1):52-4. .

Metrics

Downloads

Download data is not yet available.
Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright (c) 2026 M Harouna Amadou, L Rabiou Kaka, S Kadri, A Hachimou, A Ibrahim, A Ibrahim Mamadou, O Amadou, C Maidaoualé, I Georges Thomas, M Doutchi